High jaundice does not usually cause café-au-lait spots. Café-au-lait spots are brown patches that can be found at birth or shortly after birth, and high jaundice does not usually cause café-au-lait spots. Café au lait is a hyperpigmented skin disease that occurs on the face and trunk and can increase in size with age. Cafe au lait spots may be caused by neurofibromatosis, Albright syndrome, mottled disease, Fanconi anemia, dwarfism, ataxia telangiectasia, and so on. Infants born with high jaundice usually show symptoms such as yellow skin and yellow sclera. Therefore, high jaundice does not cause café-au-lait spots, and it is recommended to consult a doctor in time to identify the cause of the disease and then follow the doctor’s instructions to give standardized treatment.