There are many symptoms of liver and gallbladder diseases, such as epigastric pain, jaundice, fever, ascites, epigastric mass and so on. 1. Epigastric pain: epigastric pain is the most common symptom of liver and gallbladder diseases, and the pain characteristics of different diseases are different. Chronic hepatitis, chronic cholecystitis, gallbladder stones mostly manifest as hidden pain in the right upper abdomen; gallbladder stones embedded in the gallbladder duct, acute cholecystitis, acute cholangitis will have severe pain in the right upper abdomen; liver cancer can appear as distending pain in the liver area. 2. Jaundice: Jaundice is the yellowing of skin and mucous membranes caused by elevation of serum bilirubin. Various serious liver diseases can seriously affect liver function and lead to hepatocellular jaundice, and poor bile excretion caused by obstruction of common bile duct can lead to obstructive jaundice. 3. Ascites: deterioration of liver function is the most common cause of ascites, which is related to the decrease of albumin synthesis in hepatic insufficiency, the increase of hydrostatic pressure in gastrointestinal capillaries caused by the obstruction of portal venous reflux, and the obstruction of lymphatic reflux in gastrointestinal tract. 4. Upper abdominal mass: liver cancer, cholangiocarcinoma, gallbladder cancer can have upper abdominal mass, which is often a manifestation of advanced stage of tumor. 5. Fever: all kinds of liver and biliary tract infections will cause fever, which is usually high fever with chills, such as acute cholecystitis, acute pyogenic cholangitis, liver abscess, etc. In addition to the above symptoms, other possible symptoms of liver and biliary diseases include bleeding tendency, endocrine disorders, loss of appetite, nausea and vomiting, and malnutrition.