Positive skin test and negative tuberculosis antibody may be tuberculosis, but there may be false-positive and false-negative results, so it is necessary to combine with clinical symptoms and the presence of abnormalities in the lung X-ray, CT, etc. to make a comprehensive judgment. Skin test is to determine whether the body is infected with Mycobacterium tuberculosis through intradermal injection of tuberculin. If the skin test is positive, it indicates that tuberculosis may be present, but there are false-positive cases in this test. Negative tuberculosis antibody is mostly due to the fact that the patient is infected with Mycobacterium tuberculosis before the body is stimulated to produce tuberculosis antibody, so it generally suggests that the patient does not have tuberculosis. However, it is also possible that due to recent infection, not enough antibodies have been produced, or there is a failure of reagents, improper storage of specimens, etc., which may lead to false negatives. Therefore, a positive skin test and negative TB antibody does not necessarily mean that the patient has TB. It is necessary to take into account the patient’s clinical symptoms, such as cough, fatigue and low-grade fever, as well as the presence of typical TB-like lesions in the lungs on X-rays and CT scanning to make a comprehensive judgment. If you have a positive skin test and negative TB antibody after examination, you should go to the hospital in time to complete the examination, and if the diagnosis of tuberculosis is confirmed, you should go to the hospital in time for treatment under the guidance of the doctor.