There are many causes of male dysgenesis, which should be treated promptly. Supplemental growth hormone drugs need to be standardized under the guidance of a doctor. Male hypoplasia can be caused by hypothalamic-pituitary dysfunction, hereditary growth hormone deficiency, primary hypothyroidism, and gonadal axis dysfunction. 1. Hypothalamic-pituitary dysfunction: treat the primary hypothalamic and pituitary lesions first, and then carry out replacement therapy, such as growth hormone supplementation. 2. Hereditary growth hormone deficiency: it can be treated with medication, such as growth hormone drugs, and sex hormones such as testosterone can be used if the bone age reaches 12 years or older. 3. Primary hypothyroidism: thyroid hormone replacement therapy such as levothyroxine tablets. 4. Patients with growth hormone deficiency associated with gonadal axis dysfunction can be injected with long-acting testosterone enanthate. The use of drugs must follow the doctor’s instructions, not blindly use their own drugs, so as not to cause adverse consequences.