Acne on the face is generally referred to as acne in medical terms, and zinc gluconate is generally useful for acne sufferers. Taking zinc gluconate can replenish the body’s essential zinc. As an essential trace element, zinc plays an important role in many physiological processes in the body, such as anti-inflammatory, wound healing, and regulation of oil secretion. Therefore, proper zinc supplementation as prescribed by the doctor is useful for acne patients. It should be noted that adverse reactions such as mild nausea, constipation, and indigestion may occur after administration of the drug, so it is recommended to take it after meals to minimize gastrointestinal irritation. In addition, combining it with milk, calcium and aluminum salts should be avoided, and it is contraindicated for those who are allergic to the product. If acne patients want to take zinc gluconate, it is recommended to go to a regular hospital to consult a doctor and use the medication under the doctor’s guidance.