Cholecystectomy generally does not cause elevated globulin, if globulin appears to be elevated, it may be some kind of disease in the body, which causes increased immune function. Globulin is a protein in human plasma, also known as immunoglobulin, which has an immunoprotective effect against the invasion of foreign germs and microorganisms. It may be elevated globulin caused by liver disease, infectious disease, autoimmune disease, and cholecystectomy does not generally cause elevated globulin, and generally does not cause obvious symptoms, and diarrhea, abdominal distension, and other symptoms may be seen in some people. If the globulin is elevated, it is necessary to clarify which disease causes the globulin to be elevated, if it is caused by viral hepatitis, it is necessary to take drugs such as entecavir under the guidance of the doctor for treatment, if it is a rheumatoid disease caused by high globulin, it is possible to take glucocorticosteroids and so on under the guidance of the doctor for treatment. If the globulin is elevated, you need to go to the hospital in time and follow the doctor’s instructions to use drugs.