How to check for delayed excretion of bromosulfonephthalein

Delayed excretion of bromosulfophthalein is an indicator of abnormal liver function with increased serum alkaline phosphatase activity, delayed excretion of bromosulfophthalein, decreased plasma albumin, prolonged prothrombin time, and elevated indirect bilirubin abnormal globulin. Abnormal liver function is when the liver is damaged by certain pathogenic factors that can cause damage to the morphological structure of the liver and abnormal metabolism of liver function. How to check abnormal liver function? For example: digestive dysfunction, resulting in loss of appetite, anorexia, nausea, vomiting, etc.; liver cell damage, resulting in increased serum aminotransferases and other enzymes, and decreased cholinesterase, resulting in fatigue, tiredness, sleepiness, etc.; abnormal bile pigment metabolism, resulting in jaundice; impaired glucose metabolism, resulting in changes in blood lipid content, reduced cholesterol synthesis and esterification; fatty Disorders of metabolism can lead to fatty liver; disorders of albumin synthesis can lead to ascites and pleural fluid in severe cases; disorders of vitamin metabolism can lead to rough skin, night blindness, inflammation of lips and tongue, swelling, skin bleeding, osteoporosis, etc.; disorders of coagulation factor synthesis can lead to gum bleeding, nose bleeding, etc.; abnormal hormone metabolism can lead to loss of libido, menstrual disorders, dilation of small skin arteries, spider nevus, liver palm, dark face, etc. (2) Auxiliary examination 2, auxiliary tests (1) glutamic-alanine transaminase (ALT, GPT) reference value 0.0-40U/L. It is the main item to diagnose hepatocellular parenchymal damage, and its level is often parallel to the severity of the disease. ALT can be elevated in both acute hepatitis and chronic hepatitis with cirrhotic activity. However, ALT lacks specificity and can be elevated in many liver diseases and extrahepatic disorders. In addition, there is a lack of consistency between changes in ALT activity and histological changes in liver pathology, and some patients with severe liver damage do not have elevated ALT. (2) Glutamic-oxalacetic transaminase (AST, GOT) reference value 0.0-41 U/L. AST is widely distributed in multiple tissues and organs in the body, with the highest content in the myocardium and the second highest in the liver and kidney. If the AST value is higher than the ALT, it indicates that the degree of hepatocyte damage and necrosis is more serious. If its isoenzyme is measured, it is more significant, only AST is elevated in mild liver damage, while ASTm is significantly elevated in severe damage. (3))γ-Glutamyl transpeptidase (GGT) reference value 5-50 U/L. The level of GGT in healthy people is very low (<40 units), mainly from the liver, with a little produced by the kidney, pancreas and small intestine. (GGT) is not as good as ALT in reflecting necrotic damage to hepatocytes, but it has some significance in identifying jaundice, poor excretion in the liver (intrahepatic obstruction) and extrahepatic obstruction, as well as cirrhosis, liver tumor toxic liver disease, alcoholic liver disease, fatty liver, etc. It can be elevated. (4) Alkaline phosphatase (ALP, AKP) reference value 15-121 U/L. Consists of more than three isoenzymes, i.e., hepatic, intestinal (minimal) and placental (only seen in mid- to late-term pregnant women), and a portion from bone. ALP is excreted via the biliary tract. Thus, the excretion of ALP can be increased by liver disorders, biliary disorders and bone disorders. Normal reference value (30—90). (5) Total bile acid (TBA) reference value 0-12umol/L. (6) Total protein (TP) reference value 60-85g/L, albumin (Alb, A) reference value 40-55g/, L globulin (Glb, G) reference value 20-30g/L. Total protein (TP), albumin (A), globulin (G): chronic hepatitis, cirrhosis often appear albumin (7) Total bilirubin (TP), albumin (A), globulin (G): in chronic hepatitis and cirrhosis, albumin often decreases while globulin increases, inverting the A/G ratio. (7) Total bilirubin (TBil) reference value 0-20umol/L, direct bilirubin (DBil) reference value 0.0-5.6umol/L, indirect bilirubin (IBil) reference value 1.7-17.3umol/L. When jaundice occurs in liver disease, both TB and Bc can be elevated to varying degrees, and if Bc is significantly elevated, it is suggestive of obstructive jaundice. (8) AFP reference value <25ug/L (25ng/mL) in adults and <39ug/L (39ng/mL) in pediatric patients (3 weeks to 6 months).