Gallbladder stones 2cm can be observed conservatively if there are no symptoms or complications and no high-risk factors, and surgery is not required for the time being. Gallbladder stones are a very common disease in clinical practice, and most patients have no obvious symptoms and are only found during physical examination. The latest opinion suggests that for asymptomatic adult patients with gallbladder stones, they can decide whether to have surgical or non-surgical treatment according to their own conditions, and if they are not operated for the time being, they need to be followed up regularly for observation. In case of acute cholecystitis, biliary colic, bile duct stones, etc., surgical treatment is required. For asymptomatic gallbladder stones, surgical treatment should be considered if the patient is combined with the following high-risk factors: a large number of stones with a diameter of ≥2cm, calcification of the gallbladder wall or porcelain gallbladder, accompanied by gallbladder polyps with a diameter of ≥1cm, and accompanied by a thickening of the gallbladder wall of ＞3㎜. Patients with gallbladder stones 2cm in diameter are recommended to go to the hospital as soon as possible, and consult a professional doctor to make a scientific and reasonable treatment or follow-up plan.