The penis glans has particles to consider is acromegaly, pearly penile papules as well as eczema and other causes. 1. Condyloma acuminatum: male condyloma acuminatum is a benign proliferative lesion caused by human papilloma virus infection, mainly invading the genitals, perineum and anus, etc. Condyloma acuminatum occurs in the male genitals and perianal area, and can be seen in the foreskin, the ligament, the glans, the urethral opening and so on. 2. pearly penile papules: a common mucosal disease, usually asymptomatic, occasionally found in the bath or urination. The common site is around the head of the penis or the coronal sulcus, with pearly white, yellow or red translucent papules. 3. Eczema: glans skin mucous membrane eczema is generally and allergic factors are related, but also may be due to bacterial viral infections as well as unclean sexual behavior and other reasons, thus causing the phenomenon of penile glans with particles. Patients with the phenomenon of penile glans particles, it is recommended to go to the regular hospital as soon as possible for examination, clear diagnosis and treatment.