Knee edema is treated differently according to the different causes, the common causes are infection, gout, knee synovitis and so on, which need to be targeted treatment under the guidance of the doctor, such as proper rest, medication and so on. 1. Infection: because of trauma, skin breakage, etc., resulting in soft tissue infection, which causes knee swelling, fever, pain and other symptoms, need to improve the blood routine, bacterial culture and other tests, the use of antibiotics, such as cephalosporin antibiotics for anti-infection treatment. 2. Gout: acute gout can also appear knee swelling, pain, fever and other symptoms, you can use colchicine anti-inflammatory pain, febuxostat to reduce uric acid, if necessary, you can extract the knee joint fluid to reduce swelling. 3. Knee synovitis: Knee synovitis is caused by trauma and prolonged weight-bearing, which can also lead to knee swelling. You can rest appropriately, use non-steroidal anti-inflammatory drugs, such as acetylchlorophenic acid extended-release tablets to reduce inflammation and relieve pain, and if there is more fluid in the joints, you need to make a puncture to extract fluid. There are more causes of knee edema, it may also be related to kidney failure, heart disease such as cardiac failure, it is recommended to consult a doctor in time, under the guidance of the doctor.