There is no best treatment for impotence and premature ejaculation, patients need to follow the doctor’s instructions for medication or surgical treatment according to their own situation. 1. Impotence: Erectile dysfunction. Usually erectile dysfunction can be prescribed with sildenafil, tadalafil and other phosphodiesterase type 5 inhibitors, if due to the decline in the level of androgen, then need to supplement androgen. For those who are not satisfied with the effect of drug treatment, they can also be injected with intracavernous penile injection therapy, and commonly used drugs include prostaglandin, phentolamine, and so on. In addition to the above treatments, some people with erectile dysfunction can also use penile prosthesis implantation, penile artery reconstruction and other surgical treatments, as well as take the vacuum erection device therapy. 2. Premature ejaculation: Premature ejaculation can be treated with selective 5-hydroxytryptamine reuptake inhibitors such as dapoxetine, paroxetine, sertraline and other anesthesia drugs such as local application of lidocaine and proparacaine. In addition to drug treatment, some patients take extrusion method, stop-movement method and other behavioral therapy and psychotherapy, but also feasible dorsal penile nerve selection cut off surgery. It is recommended that impotence, premature ejaculation actively cooperate with the doctor’s treatment, not to indiscriminate use of drugs or prescriptions. Daily attention to personal hygiene care, appropriate abstinence from sex.