High urine sugar 4 + may be caused by physiological factors, may also be caused by diabetes, kidney disease and other disease factors, but also need to be analyzed in the context of the specific situation. Physiological factors caused by the general does not affect life, disease-induced urinary glucose after active treatment of the primary disease can also achieve long-term survival, and even does not affect life. 1. Physiological: when a short period of time a large number of sugary foods, will cause blood glucose transiently over the renal glucose threshold resulting in a positive urine glucose; stress urine glucose, seen in craniocerebral trauma, extensive burns, emotional excitement and other situations, resulting in temporary hyperglycemia and glycosuria. This situation leads to high urine sugar generally does not affect life expectancy. 2. Pathological: diabetes mellitus, renal disease, Cushing’s syndrome, hyperthyroidism and other diseases can also cause positive glucose, should be actively treating the primary pathology, high glucose 4+ can not predict the impact on life expectancy based on glucose alone. Patients with 4+ urine glucose are advised to go to the hospital after eliminating physiological factors.