Rosuvastatin side effects may usually manifest in 5 hours, and potential side effects on skeletal muscle, liver, etc. may require longer observation and monitoring. Clinically, Rosuvastatin enters the gastrointestinal tract after administration and is then taken up by the liver with some selectivity. Since the liver is the target organ for cholesterol-lowering action, hepatic uptake can achieve the effect of lowering cholesterol in serum lipids. It is mainly used in the treatment of primary hypercholesterolemia and mixed dyslipidemia. The drug can reach the peak concentration of the drug about 5 hours after taking, at this time may appear dizziness, headache, constipation, nausea, abdominal pain, weakness, myalgia and other discomforts. The drug is excreted in the urine about 19 hours after taking it, and the related side effects gradually disappear. The drug may cause damage to skeletal muscle, resulting in increased creatine kinase, muscle pain, weakness and other symptoms, if there is no obvious discomfort, usually do not need to routinely monitor creatine kinase levels. The drug may cause elevation of liver transaminases, generally monitor liver function levels before and 3 months after use of the drug, if serum transaminase levels are higher than the upper limit of the normal value of more than 3 times, the use of the drug should be suspended. The use of the drug is prohibited for those who are allergic to the components of the drug, active liver disease, severe renal impairment. While taking the drug, it is necessary to monitor renal function, as well as to periodically review serum lipids. And pregnant and lactating women need to use the drug under medical supervision. If side effects occur after taking Rosuvastatin, it is recommended to stop taking the drug and visit a doctor.