The normal range of urine specific gravity is generally 1.015~1.025, urine specific gravity 1.005 is the case of low urine specific gravity, also called hypotonic urine or hypospecific urine. Hypospadias can occur in physiological conditions, patients taking diuretics can also appear hypospadias, hypospadias can also be seen in a variety of diseases such as chronic renal failure, renal tubular disease, uremic syndrome, and so on. 1. physiological situation: normal infants and young children due to the renal tubules are not fully developed, can appear low specific gravity urine; older people due to the decline in renal concentrating function, can also appear low specific gravity urine; when the normal people drink more water, the urine is diluted, can also appear low specific gravity urine. 2. Patients taking diuretics: For patients using diuretics such as furosemide, hydrochlorothiazide, etc., the increase in the number of urination and the volume of urination can appear hypospadias. 3. Chronic renal failure: in the early stage of chronic renal failure, due to the damage of renal tubular epithelial cells, resulting in decreased concentrating function, which leads to increased nocturia and hypospecific gravity urine. 4. Renal tubular diseases: renal tubular diseases such as renal tubular acidosis, Fanconi syndrome, etc., due to the decrease of tubular urine concentration function, resulting in polyuria and hypospecific gravity urine. 5. Uremia: due to a decrease in the secretion of antidiuretic hormone, leading to a decrease in the reabsorption function of the kidneys, resulting in polyuria, hypospecific gravity urine. There are other reasons for the decrease in specific gravity of urine, you should go to the relevant departments of the regular hospital, the physician will make a comprehensive judgment based on the patient’s specific situation and test results.