Urinary light chain is the light chain portion of immunoglobulin excreted in the urine through the kidneys, with the heavy chain to form the protein, which is a component of certain proteins. Urinary light chain protein, known as weekly proteinuria, is tested in the clinic to diagnose diseases such as multiple myeloma.
When myeloma cells synthesize abnormal immunoglobulins, there is an excess of light chains, which can freely pass through the glomerular filtration membrane, resulting in an excess of light chains in the urine, i.e., periplasmic proteinuria or light-chain urine, so light chains are also known as periplasmic proteins, which are also a type of protein.
When there is an increase in light chains in the urine, it may be associated with diseases such as multiple myeloma, macroglobulinemia, and primary amyloidosis.
When positive peripheral proteinuria occurs, it is necessary to go to a regular hospital in time, to clarify the cause of the disease under the guidance of the doctor, and to actively treat it.