PSA includes tPSA (total prostate-specific antigen) and fPSA (free prostate-specific antigen), either tPSA or fPSA of 22ng/ml suggests that prostate cancer is more likely, but cannot confirm the diagnosis. PSA is a prostate-specific antigen found in the epithelial cells of prostate ducts. tPSA should be <4ng/ml, fPSA should be <0.8ng/ml, and fPSA/tPSA should be <0.25. tPSA will be elevated to different degrees in benign diseases such as prostate cancer and prostatitis. Generally speaking, when tPSA>10ng/ml, the possibility of prostate cancer is high, and when tPSA is between 4~10ng/ml, it is necessary to identify benign and malignant diseases of the prostate with reference to fPSA/tPSA. If tPSA is 22ng/ml, the patient is more likely to have prostate cancer, if fPSA is 22ng/ml, tPSA must be >22ng/ml, the patient is still more likely to have prostate cancer. It is recommended that the patient should consult the doctor in time, follow the doctor’s instructions for further examination, and if necessary, carry out prostate imaging and pathologic examination to clarify the cause of the disease and actively treat it.