Vague pain below the right rib cage is associated with many conditions, such as liver, biliary tract pathology and gastroduodenal pathology or cardiopulmonary pathology. Therefore, it is difficult to give an accurate diagnosis based on the pain below the right rib cage alone. The doctor needs to use the patient’s description and perform certain tests, such as ultrasound, to observe whether there are stones, polyps, or inflammation in the patient’s gallbladder, liver, or bile ducts to clarify the cause of the patient’s symptoms of discomfort. In addition, gastroscopy can be performed to observe whether there are ulcers, gastritis and duodenitis in the patient’s stomach and duodenum, and an electrocardiogram or chest X-ray can be done to rule out myocardial ischemia, myocardial infarction or inflammation of the lungs and pleural effusion. Only by finding the obvious lesion and the cause of the occurrence of uncomfortable symptoms and taking the appropriate measures can the symptoms be eliminated, such as removing the diseased gallbladder and giving medications to protect the stomach and control lung infections.