Pustules in the eyelid area are usually caused by a bacterial infection that is not controlled in time, leading to local tissue necrosis. The most common causes are granuloma and sebaceous adenitis. 1. Erythroderma: caused by bacterial infection of the eyelid gland or eyelash follicle inside the eyelid. 2. Sebaceous adenitis: caused by a bacterial infection of the sebaceous glands. Both will cause redness, swelling and pain in the eye area. Once the inflammation is not able to be treated in time and continues to aggravate, it will cause local tissue necrosis and pus formation, which will be manifested as pustules. Pus blisters in the eyelid area, should be timely to the hospital ophthalmology treatment, through incision and drainage of pus release pus, and under the guidance of the doctor for drug treatment.