A high white blood cell count on physical examination also needs to be combined with further physical examination and other tests. In many patients, this is secondary to skin or soft tissue infections, and can also occur in the lungs. Many patients have upper respiratory tract infections that are complicated by cough, sputum, chest pain, or chest tightness. For community-acquired pneumonia, cephalosporins or quinolones can be empirically selected for intravenous antimicrobial input. The patient should also be advised to perform deep breathing exercises to promote coughing and sputum excretion during treatment, as well as nebulized inhalation therapy and appropriate dietary supplementation.