Platelet 450 x 10^9/L is a mild increase in platelet count, and whether platelet 450 x 10^9/L needs treatment or not needs to be analyzed in the context of the specific situation. Young patients with reactive increase in platelet count due to concurrent lung infection usually do not need to be given special treatment in this case. After anti-infection treatment, the pneumonia is controlled and the platelet count will gradually decrease. However, if it is an elderly patient, who has high blood fat, high blood sugar and other diseases, if the platelet reactivity increase caused by lung infection, it may induce thrombosis and embolism, resulting in cerebral thrombosis, coronary heart disease, it is necessary to give appropriate antiplatelet therapy, the most commonly used drug is aspirin, and in serious cases even need to be treated with Polivir maintenance therapy. Therefore, whether platelets 450×10^9/L need to be treated needs to be analyzed with the specific conditions of the patient.