The causes of hiccups are both physiologic and disease-related. Physiological causes include overeating, eating irritating food, etc. Pathological causes include reflux esophagitis, mediastinal tumor, esophageal cancer, gastritis, etc. 1. Physiological causes: such as overeating, getting cold, eating stimulating food (chili, mustard), etc., which can trigger diaphragmatic spasm and hiccup symptoms. 2. Disease causes: such as reflux esophagitis can also have acid reflux, heartburn and other symptoms; such as mediastinal tumors can also have chest tightness, chest pain and other symptoms; such as esophageal cancer can also have weight loss, dysphagia and other symptoms; such as gastritis can also have stomach pain, acid reflux and other symptoms. Frequent hiccups may be caused by other reasons, such as central nervous system diseases, such as meningitis, brain tumors, pneumonia, lung tumors and other diseases, and it is recommended to actively consult the doctor for a clear diagnosis.