The absence of antibodies to hepatitis B refers to the absence of hepatitis B surface antibodies. These are protective antibodies that are given after the hepatitis B vaccination in order for the body to produce hepatitis B surface antibodies. The absence of surface antibodies means that there is no immunity to the hepatitis B virus. If all the other items in the five hepatitis B tests are negative, such a person can receive the hepatitis B vaccine. If the absence of surface antibodies is accompanied by a positive hepatitis B surface antigen, it means that the person is currently a hepatitis B patient and there is no need to get the hepatitis B vaccine, because the hepatitis B vaccine can only be used as a prevention and its current use in treatment is very limited. The hepatitis B vaccine is also not recommended if it is accompanied by a positive hepatitis B core antibody or e antibody and no hepatitis B surface antibody. Because previous infections with the hepatitis B virus have not allowed the body to produce hepatitis B surface antibodies, and the immunogenicity of the hepatitis B vaccine is much lower than that of the hepatitis B virus itself, the hepatitis B vaccination will not allow the body to produce the appropriate surface antibodies, although there are no side effects.