Experience and lessons learned: 1, early esophageal cancer can be treated by purely radical surgery, postoperative chemotherapy or radiotherapy is not beneficial, but increases toxic side effects and treatment costs and affects survival quality, excessive treatment should be avoided; 2, patients who are not suitable for surgery, random surgery will lead to cancer cells will accelerate the growth and metastasis, the author often encountered in the clinical esophageal palliative surgery, surgical trauma causes immunity decline, tumor cell dissemination, and 3. In cervical and upper thoracic esophageal cancer, there are trachea, important nerves and large blood vessels around the tumor, so it is difficult to remove the tumor and the lymph nodes are not easy to be cleared, and even the whole larynx has to be removed. The author met a case of cervical esophageal cancer patient, who had an anastomotic fistula during the surgery and the whole larynx was removed together. 4, the remission period of chemotherapy alone is short, generally not more than 6 months on relapse progression, for patients with local progressive stage, it is recommended that chemotherapy should not exceed 2 cycles with radiotherapy, otherwise the efficacy is poor, and the complications of treatment are aggravated. The author met a case of locally progressive upper thoracic esophageal cancer who was treated with chemotherapy for 2 cycles in a foreign hospital, the tumor shrank, and then continued chemotherapy for 2 cycles, but the tumor increased, and then changed the plan to chemotherapy for 2 cycles, and the disease progressed to the point that he could not eat, and he had a gastrostomy with nutritional infusion before he was transferred to our department for radiotherapy, and finally he could eat, but the patient’s physical quality obviously decreased, and the quality of survival was poor, and the treatment cost was very high. 5. During radiotherapy, it is necessary to regularly check blood picture, liver and kidney function as well as esophageal X-ray and CT film, etc. to closely observe the condition and timely treat the symptoms to avoid complications as much as possible. In conclusion, through strict standardized and individualized treatment of esophageal cancer, it not only improves survival rate, reduces recurrence and metastasis rate, and alleviates toxic and side effects, but also avoids treatment cost and quality of life decline brought by over-treatment of early post-operative patients. The success of each treatment case preserves a family, promotes family harmony and social stability, and has good social and economic benefits.