Patients with intestinal tuberculosis are generally not contagious to their family members if they do not have a primary lesion, but if they have a primary lesion, such as open tuberculosis, there is still a possibility of contagion to family members. Intestinal tuberculosis is mainly an infection caused by Mycobacterium tuberculosis invading the intestinal tract, and most of the patients are triggered by Mycobacterium tuberculosis human type, and its transmission is through oral transmission and hematogenous dissemination. Generally, pulmonary tuberculosis is the primary lesion, in which patients with open pulmonary tuberculosis or laryngeal tuberculosis will swallow sputum containing Mycobacterium tuberculosis, which will induce intestinal tuberculosis. Primary intestinal tuberculosis can also be induced by sharing tableware with patients with open tuberculosis or by inadequate sterilization of tableware. If the patient has open tuberculosis and his/her family members are constipated or immunocompromised, the family members are at higher risk of contracting intestinal tuberculosis, which can be induced by invasion of tubercle bacilli. The patient’s family members can prevent infection by vaccinating with BCG vaccine, wearing masks and avoiding close contact with the patient, and encouraging the patient to consult a specialized infectious disease hospital for active treatment. It is recommended that patients with intestinal tuberculosis strictly under the guidance of the doctor for targeted treatment, patients’ families to do a good job of prevention.