Leg numbness should be alert to central or peripheral neuropathy, lumbar spine lesions, vascular lesions, etc., it is recommended to go to the hospital in a timely manner to diagnose the cause of the disease. 1. Neuropathy leading to leg numbness: ① central neuropathy: such as cerebral infarction, cerebral hemorrhage, cerebral hypoperfusion and other diseases leading to numbness of the legs, through the cranial CT, MRI and other tests to detect; ② peripheral neuropathy: such as diabetic patients combined with peripheral neuropathy leading to numbness of the legs, can be through the electromyography, glycated hemoglobin and other tests to detect. 2. Lumbar spine lesions lead to leg numbness: such as lumbar disc herniation, compression of the nerve root caused by leg numbness, lumbar spine through magnetic resonance and other tests to detect. 3. Vascular lesions lead to leg numbness: such as lower extremity arterial stenosis, atherosclerosis, thrombotic vasculitis, etc., can be detected by lower extremity ultrasound and other tests. There are many other diseases that cause numbness of the legs, it is recommended that when numbness of the legs in a timely manner to seek medical treatment, the professional doctor according to the individual situation to judge, choose the appropriate examination and develop individualized treatment plan, do not blindly use drugs, so as not to delay the condition.