High bilirubin in 10-year-old children is mostly due to abnormal bilirubin metabolism, which is commonly caused by liver diseases, bile duct diseases, blood transfusion reactions and so on. If bilirubin is found to be high in 10-year-old children, they should follow medical advice for further examination and active treatment. 1. liver diseases: the liver plays an important role in the metabolism of bilirubin, viral hepatitis, cirrhosis, toxic hepatitis, etc., can lead to liver cell damage in children, resulting in high bilirubin, low fever, loss of appetite, nausea, vomiting and other symptoms, such children can use polyphosphoinositide Choline, reduced glutathione and other drugs for treatment; 2. Bile duct diseases: If children have gallbladder stones, bile duct stones, etc., the stones may compress the common bile duct, thus causing bilirubin to rise. Due to different obstruction sites and different severity, bilirubin can have different degrees of elevation. Such patients should be treated under the guidance of doctors. If gallbladder stones are found, smaller stones can be treated actively with ursodeoxycholic acid capsules, while larger stones can be surgically removed; 3. Blood transfusion reaction: If the blood type does not match during the transfusion, a blood transfusion reaction will occur, at which time hemolysis may occur, and bilirubin will increase rapidly with the rupture of red blood cells, which is beyond the normal processing range of the liver and may result in Jaundice, at this time immediately stop the transfusion, retain the remaining blood, find the cause of hemolysis, symptomatic treatment; 4, other: genitourinary system diseases, such as paroxysmal hemoglobinuria or visceral bleeding, when serious can also make children’s bilirubin elevated.