Hepatobiliary stones refer to intrahepatic bile duct stones. If the size of the hepatic bile duct stone is 6mm and the patient is asymptomatic, it is not serious. If there are obvious symptoms, it is more serious. Intrahepatic bile duct stones are a common liver and gallbladder disease, and determining whether intrahepatic bile duct stones size 6mm are serious needs to be determined on a case-by-case basis and cannot be generalized. If the size of intrahepatic bile duct stones is 6mm and the patient has no obvious clinical symptoms, it may not be serious in general and there is no need to worry too much, the patient needs to follow up regularly and no treatment is needed for the time being. However, if the size of intrahepatic bile duct stones is 6mm and there are obvious symptoms such as abdominal pain, jaundice, belching (hiccups), aversion to grease, etc., then it is relatively more serious, and the patient needs to actively cooperate with the doctor to take standardized treatment measures. In addition, because the prognosis of this disease is related to the duration of the disease, so patients need to cooperate with doctors as soon as possible for standardized treatment. To summarize, patients with intrahepatic bile duct stones can improve their prognosis through “early detection, early diagnosis and early treatment”, and at the same time, they need to strengthen their daily life management and follow up on time.