Ebastine tablets can be used with montelukast, both are anti-allergic drugs, but the mechanism of action is different, can be taken together, but it is generally recommended to take a single dose, the effect is not good and then a combination of drugs. Ebastine tablets are a long-acting, highly selective histamine H-receptor blocker with no anticholinergic effect. It is indicated for allergic rhinitis with or without allergic conjunctivitis. Symptomatic treatment of chronic idiopathic urticaria. It is contraindicated in patients with hypersensitivity to ebastine or any of the components of the tablets, no data have been obtained on the use of the drug in lactation, pregnant women, and may be associated with adverse symptoms such as headache and dry mouth. Montelukast sodium has a high affinity and selectivity for cysteinyl leukotriene receptors. Montelukast inhibits the physiologic effects resulting from cysteinyl leukotriene receptor binding without any receptor agonist activity. It is indicated for the prophylaxis and long-term treatment of asthma as well as seasonal allergic rhinitis and perennial allergic rhinitis. Avoid using the drug during lactation and pregnancy. It is contraindicated in patients who are allergic to ebastine or any of the ingredients in the tablets. Adverse reactions such as infection and thrombocytopenia may occur. All of the above medicines are prescription drugs for reference only, and the specific dosage should follow the doctor’s instructions. Do not self-medicate to avoid serious adverse reactions.