Other medications such as omeprazole, domperidone, and compounded digestive enzymes may be needed after quadruple therapy depending on the condition. The so-called quadruple therapy refers to anti-Helicobacter pylori treatment. Even if H. pylori eradication is successful, it does not mean that the symptoms will disappear, and there is a possibility that medications are still needed for symptomatic treatment, which are commonly available, such as proton pump inhibitors, gastrointestinal dynamics, digestive aids, and so on. 1. Proton pump inhibitors: can control gastric acid secretion, improve acid reflux, stomach pain and other symptoms, common omeprazole, lansoprazole and so on. 2. Gastrointestinal tract power agent: it can increase the power of gastrointestinal tract and improve the symptoms of gastric distension, acid reflux, etc. Commonly, there are domperidone and mosapride. 3. Digestive aids: can promote the secretion of digestive juices, improve gastric distention, belching (burping) and other symptoms, commonly found in compound digestive enzymes, mitomycin pancreatic enzyme tablets and so on. For whether to take other drugs after the quadruple therapy, it is recommended that the patient consult the doctor in time, and the doctor will determine according to the individual situation.