Free fatty acids are substances in human blood that can be absorbed and utilized by cardiac muscle, skeletal muscle and other tissues, and can be involved in metabolism, cell proliferation, hormone regulation and inflammatory response, etc. They are the most active metabolites, and the determination of free fatty acid profiles can reflect some of the risks of suffering from cardiovascular disease, metabolic syndrome, liver disease, diabetes and other diseases.
Cardiovascular disease: high concentration of free fatty acids can cause hyperfibrinogenemia, fibrinogen deposition in the vessel wall, antagonistic effect on heparin. Contribute to platelet anti-red blood cell agglutination, so that the arteries toward atherosclerosis.
Metabolic syndrome: free fatty acids are the most active metabolic lipids in human body, half-life is only 2~3 minutes, more sensitive response to lipid metabolism disorder indicators.
Diabetes mellitus: Elevated free fatty acid concentration can aggravate insulin resistance and β-cell dysfunction through various mechanisms, thus causing abnormal blood glucose.
Liver disease: High free fatty acidemia may also damage liver cells, and the occurrence of fatty liver is closely related to lipid metabolism disorders.
If the results of free fatty acid profile are abnormal, patients can go to the endocrinology department of regular hospitals and other related departments for further diagnosis and treatment.