Leg pain after standing for a long time needs to be treated according to the cause, usually muscle fatigue, meniscus injury, osteoarthritis and rheumatoid arthritis, etc. Commonly used general treatment, medication, surgical treatment. 1. Muscle fatigue: leg pain after standing for a long time may be due to the accumulation of lactic acid in the leg muscles because of fatigue. In this case, there is no organic lesion in the leg, and it can be recovered through general treatment, rest, hot compresses, massage and physiotherapy. 2. Meniscus injury: mild to moderate meniscus injury can be treated conservatively, through the plaster fixed for 1 to 2 months meniscus can be restored to the normal state, if it is a serious meniscus injury, meniscus tear, need to carry out meniscus under the microscope suture surgery or meniscoplasty. 3. Osteoarthritis: Osteoarthritis is a degenerative disease. Leg pain caused by osteoarthritis can be relieved by oral non-steroidal anti-inflammatory drugs, such as celecoxib. Joint replacement may be needed in severe cases. 4. Rheumatoid arthritis: Rheumatoid arthritis is a kind of synovial proliferative inflammation, which is usually treated with glucocorticoid therapy such as prednisone. The above drugs need to be used under the guidance of a doctor.