In case of hematospermia caused by seminal vesiculitis, prostatitis, etc., it is usually necessary to take moxifloxacin for about 1 to 2 weeks. The specific time of taking it is decided according to the severity of the patient’s condition. Moxifloxacin is a fluoroquinolone antibacterial drug for acute sinusitis, acute exacerbation of chronic bronchitis, community-acquired pneumonia, skin and soft tissue infections. Moxifloxacin can also be used to treat hematochezia if it is caused by seminal vesiculitis or prostatitis due to pathogenic bacteria that are sensitive to moxifloxacin, and it usually needs to be taken for about 1 to 2 weeks. Common adverse reactions to moxifloxacin include headache, malaise, loss of appetite, dry mouth and nausea, dyspepsia, and allergic dermatitis. Moxifloxacin is contraindicated for people with known hypersensitivity to any of the tablet’s ingredients or other quinolones. It is also contraindicated in children younger than 18 years of age and pregnant women. Hematochezia can also be caused by non-infectious diseases such as tumors, so patients who experience hematochezia are advised to seek medical attention to identify the cause and treat it.