The first world survey of drug-resistant tuberculosis conducted by the World Health Organization (WHO) showed that of the 6 to 8 million new cases recorded each year, 10% of patients were resistant to at least one TB drug and 2% were resistant to more than two. Multi-drug resistant TB was found in all 35 countries surveyed. The most severe cases were in India, Russia, Latvia, Estonia, Dominica, and Argentina. These alarming new figures confirm that drug-resistant TB is quietly occurring in several countries and regions of the world. If not taken seriously, drug-resistant tuberculosis will soon spread, a warning the World Health Organization has issued to the world in recent years. According to experts, drug-resistant tuberculosis has also been on the rise in recent years in China, especially in the elderly relapsed TB patient population. Sometimes the treatment with triple or quadruple anti-tuberculosis drugs is still ineffective, and if the disease continues to progress, it does affect health or endanger life. Tuberculosis has long been recorded in Chinese medicine as “pulmonary consumption”, and today’s drug-resistant tuberculosis can fall under the category of “Yin and Yang deficiency” in Chinese medicine. The main clinical symptoms are emaciation, afternoon hot flushes, generalized weakness, and sputum production or sputum with decoction. In recent years, pharmacological research on Chinese medicine has proved that many Chinese medicines have strong inhibition effect on Mycobacterium tuberculosis. For example, Bupleurum, Scutellaria baicalensis, Bacopa monniera, Paeonia lactiflora, Cordyceps sinensis, Radix et Rhizoma eucommiae, Radix et Rhizoma xanthium, Radix et Rhizoma cypress, Radix et Rhizoma dulcis, Radix et Rhizoma ichthyosporum, Radix et Rhizoma dulcisporum, Radix et Rhizoma biloba, Radix et Rhizoma gymnema spp. Treatment with anti-TB drugs can be accompanied by the use of Chinese herbs, which can increase the efficacy and prevent the emergence of drug resistance. Clinical treatment can also be combined with acupuncture or plum blossom acupuncture, which can increase the body’s immune function and accelerate metabolism, thus increasing the body’s resistance to disease and thus having a better adjunctive effect. Acupuncture can be selected from the large vertebrae, lung acupuncture point, ankle, heart acupuncture point, foot three li, three yin jiao, two times a week, three months as a course of treatment. For plum blossom acupuncture, the back acupuncture point next to the spine is mainly selected for 80 to 100 taps, with local redness. It can improve many symptoms of tuberculosis, such as cough, night sweats, hot flashes, fatigue and insomnia. For drug-resistant tuberculosis, in addition to Chinese and Western drug treatment, we should also pay attention to health and prevention: always inhale fresh air. Open the windows every morning and evening to keep the air fresh indoors, and go to outdoor woods or parks frequently to inhale more fresh air. Prevent emotional sorrow. Chinese medicine believes that sadness and lung, must be optimistic, open-minded, do not worry about sadness, and do not get angry. Pay attention to strengthen food therapy. Three meals a day, high protein, multivitamin. Such as fish, eggs, lean meat, soy products, spinach, rape, cabbage, radish, fungus, mushrooms, pear, loquat, orange, etc.. Get enough sleep and live regularly. Quit smoking and avoid alcohol, go to bed early and wake up early, and develop the habit of taking a nap at noon.