The thinning of gastric mucosa is considered to be caused by chronic atrophic gastritis. Chronic gastritis, Helicobacter pylori infection, long-term use of acid-suppressing drugs and other reasons may lead to long-term inhibition of the secretion function of the gastric mucosa wall cells and the occurrence of atrophy of the gastric mucosa thinning phenomenon. Gastroscopy can be found in the gastric mucosa of the blood vessel texture is clearer, the overall white-based. Chronic atrophic gastritis may lead to reduced secretion of gastric acid, poor absorption of nutrients and symptoms such as nausea, vomiting, emaciation, anemia, etc., and its further development may lead to intestinal metaplasia or even cancer. If gastroscopy shows thinning of the gastric mucosa, further examination of pathological biopsy, Helicobacter pylori breath test, tumor markers and other items to find the cause of the treatment under the guidance of the doctor. Avoid smoking and alcohol, eat regularly and quantitatively, do not eat cold, deep-fried, barbecue, spicy and stimulating food.