There is no best way to stop itchy toes, itchy toes may be related to physiological factors, athlete’s foot and eczema, after diagnosis is mainly for drug treatment, the causative factors are different, the medication is also different, including clotrimazole ointment, tacrolimus ointment and so on. 1. Physiological factors: for example, wear shoes and socks thicker, sweating more, sweat on the toe area caused by irritation, will cause itchy toes, should be replaced with appropriate shoes and socks, and wash your feet diligently, can be improved on their own. 2. Tinea pedis: usually associated with fungal infections, can make the local appearance of peeling, skin thickening and other symptoms, after diagnosis is mainly applied topical antifungal drug treatment, such as terbinafine hydrochloride cream, can inhibit fungi and eliminate fungi. 3. Eczema: For the itchy toes caused by eczema, which may also be accompanied by tingling and red rashes, after the diagnosis can be treated with topical glycerine lotion and tacrolimus ointment, etc. After the diagnosis, it is necessary to take oral antihistamines, such as benadryl and cetirizine. In the process of treatment, patients should follow the doctor’s instructions to use reasonable medication, do not abuse the drug treatment.