Damage to the hair follicles commonly occurs as a result of folliculitis, which should be treated with antimicrobial therapy. Other skin diseases such as androgenetic alopecia can also lead to changes in the hair follicles, which need to be treated according to the specific cause. 1. Folliculitis: bacterial infections appear folliculitis, can be used externally erythromycin ointment, mupirocin ointment and other drugs. For Malassezia infection caused by folliculitis, you can use topical ketoconazole and other antifungal drugs to treat. 2. Androgenetic alopecia: can lead to follicular miniaturization and progressive reduction of hair, can be topical topical minoxidil tincture to promote hair growth, men can be combined with oral finasteride, women can be combined with oral spironolactone and other drugs treatment. Hair follicle damage can be caused by different diseases, need to identify the cause as soon as possible, and then under the guidance of the doctor to use medication.