Standardized comprehensive treatment of head and neck tumors

Head and neck tumors mainly include laryngeal cancer, hypopharyngeal cancer, nasopharyngeal cancer, middle ear cancer, salivary gland tumors, thyroid tumors and oral and maxillofacial tumors. Head and neck tumors involve a wide range of areas and have very complex anatomical structures, and the first symptom is often enlarged metastatic nodes in the head and neck, while the symptoms of the primary lesion often appear later. Otolaryngology-head and neck surgeons are not only familiar with the anatomy and examination methods of head and neck, but also familiar with the relationship between the anatomical structures of head and neck. Therefore, otorhinolaryngology-head and neck surgeons are more comprehensive in considering head and neck tumors and have advantages that are incomparable to other specialists. For both benign and malignant head and neck tumors, surgery is still the most important treatment (except for nasopharyngeal carcinoma, but for residual lesions of nasopharyngeal carcinoma treated with radiotherapy, salvage surgery is still an important means to save the patient’s life), but the primary site of tumor in otolaryngology-head and neck surgery is often deeper, and malignant tumors often require cervical lymph node dissection, and resection of the defective site often requires This makes the surgery much more difficult. Otolaryngology-head and neck surgeons are familiar with the anatomy of the head and neck, and they can perform complete resection of primary tumors and tumors with multi-organ invasion and metastasis in all parts of the head and neck, and they also attach great importance to functional preservation surgery. In addition to surgical treatment, comprehensive standardized treatment is very important for head and neck malignant tumors. Pre-operative and post-operative radiotherapy and chemotherapy, and post-operative functional recovery treatment are important to improve the five-year survival rate of head and neck malignant tumors and improve the quality of life after surgery. Our hospital has established a head and neck tumor diagnosis and treatment collaborative group consisting of otolaryngology, radiotherapy, nuclear medicine, medical oncology and radiology. Each head and neck malignant tumor patient is discussed by the collaborative group and then a comprehensive treatment plan is formulated and standardized treatment is carried out to improve the survival rate and quality of life of patients. Laryngeal cancer is the second most common cancer of the respiratory tract after lung cancer. According to its primary site and tumor scope, our department chooses laryngeal laser surgery, partial laryngectomy, subtotal laryngectomy or total laryngectomy to cure the tumor and preserve the laryngeal function as much as possible. For middle and advanced laryngeal cancer and hypopharyngeal cancer, cervical lymph node dissection and functional reconstruction of laryngeal defect are performed at the same time. Some patients are supplemented with radiotherapy and chemotherapy before or after surgery, as well as postoperative swallowing and vocal function exercises, which improve the treatment effect and patients’ quality of life. Benign and malignant thyroid tumors together account for the first place in the incidence of head and neck tumors. With the improvement of people’s health awareness, the early consultation rate of thyroid swelling has been greatly improved. Traditional surgery often adopts intracapsular excision or simple tumor removal, which has a high recurrence rate and can easily damage the laryngeal nerve. Therefore, according to the principles of thyroid tumor diagnosis and treatment and our years of clinical experience, for thyroid masses or adenomas with unknown diagnosis, we routinely perform thyroid lobectomy on one side of the thyroid gland or one side of the gland plus isthmus under the protection of the recurrent laryngeal nerve under visualization; for malignant thyroid tumors with clear diagnosis and negative lymph nodes, we routinely perform total thyroidectomy + lymph node dissection in area VI after dissecting the recurrent laryngeal nerve; if the lymph nodes are positive, we perform lymph node dissection in the cervical side at the same time. If the lymph nodes are positive, then lateral cervical lymph node dissection is performed at the same stage, and TSH suppression therapy or combined with I131 therapy is given after surgery. This reduces the possibility of tumor recurrence and avoids the complication of postoperative hoarseness caused by surgical damage to the laryngeal nerve. Nasopharyngeal carcinoma is the malignant tumor of the head and neck with the highest incidence, and radiation therapy is still the main treatment method. However, the surgical treatment of nasopharyngeal carcinoma that recurs after adequate radiotherapy and the surgical treatment of nasopharyngeal carcinoma that remains after radiotherapy is the hot spot of research and the key to improve the survival rate of nasopharyngeal carcinoma. Our department cooperates with radiology department to explore nasal endoscopic lesion resection for patients who failed after radiotherapy for nasopharyngeal carcinoma, which reduces trauma and improves the survival rate of nasopharyngeal carcinoma patients. The most common salivary gland tumor is parotid tumor. The parotid gland is located below the earlobe, and the facial nerve, which governs the movement of facial expression muscles, passes between the deep and superficial lobes of the parotid gland. The large auricular nerve is located underneath the parotid gland and innervates the sensation of the earlobe and the posterior area of the ear. Another common complication of parotid surgery is gustatory sweating syndrome, in which the skin of the parotid area becomes flushed and sweaty when eating or drinking. For benign parotid tumors, we routinely preserve the greater auricular nerve and parotid occlusal fascia and perform partial parotidectomy or superficial parotidectomy + facial nerve dissection to reduce the occurrence of facial palsy, earlobe numbness and gustatory sweating syndrome. For malignant tumors of the parotid gland, the facial nerve is preserved as much as possible under the principle of complete tumor removal and postoperative adjuvant radiotherapy, which reduces recurrence and improves the survival rate and quality of life of patients. Parapharyngeal gap tumors refer to tumors occurring in the parapharyngeal gap. The parapharyngeal gap is a potential gap starting from the base of the skull up to the hyoid bone, with a deep location and in a complex anatomical relationship, where a variety of benign and malignant tumors can occur. Because of its small number of primary tumors, complex and diverse pathological types, hidden anatomical location and no specific symptoms, it is difficult to diagnose early and often misdiagnosed as common pharyngeal diseases. Parapharyngeal space tumors have different symptoms and signs according to their location, tumor source, growth rate, invasive characteristics and patient’s age. The main manifestations are (1) painless neck mass or swelling (2) manifestations of organ involvement: nasopharynx – obstruction of pharyngeal canal pharyngeal opening can cause tinnitus, hearing loss and middle ear effusion, etc.; oversized mass can cause nasal congestion and snoring, etc.; growth of oropharynx can cause difficulty in breathing and swallowing; compression of laryngopharynx can cause change of voice and difficulty in breathing. If the tumor grows to the pterygopalatine fossa or is located between the ascending branch of the mandible and the transverse process of the cervical vertebrae, it will cause restriction of mouth opening and even neck movement. (3) Nerve involvement and tumors originating from the nerve: neuralgia such as neck pain, pharyngeal pain or otalgia on one side; cervical sympathetic nerve involvement with characteristic Horner syndrome; vagus nerve involvement with ipsilateral vocal cord paralysis – hoarseness; inferior lingual nerve involvement with ipsilateral tongue palsy; less common paraglottic nerve involvement with corresponding nerve paralysis symptoms. Surgery is the main reliable treatment method for parapharyngeal space tumors. The main surgical approaches are lateral cervical approach, cervical-parotid approach, oropharyngeal approach and cervicomaxillary approach. Depending on the size, origin and nature of the tumor, a reasonable surgical approach can be chosen. The cervicomaxillary approach has the advantages of clear vision and adequate exposure. For large benign tumors in the parapharyngeal space or malignant tumors with infiltrative growth, the cervicomaxillary approach should be chosen when it is estimated that the tumor cannot be removed through the lateral cervical approach or the cervical-parotid approach or the radicality cannot be guaranteed. In our department, more than 10 cases of huge parapharyngeal gap tumors were resected by cervicomaxillary approach without serious complications, which is a more ideal procedure for resecting huge parapharyngeal gap tumors or malignant tumors.