Tetanus is a specific infection caused by tetanus bacillus. According to the symptoms of patients, it is divided into incubation period (no symptoms), prodromal period (muscle tension) and seizure period (continuous muscle spasm), and the symptoms of each stage are different. 1. Incubation period: The incubation period usually lasts for 4~14 days, during which patients usually have no obvious abnormal symptoms, and the incubation period may vary depending on the condition of the wound, its location and the way it is handled. 2. Prodromal stage: patients in the prodromal stage may have weakness, dizziness, restlessness and other systemic manifestations, but also paroxysmal tonicity of local muscles, spasm, the more common parts of the masticatory muscles, facial expression muscles, the neck, back, abdomen, limbs, etc., the patient may appear “bitter smile face”, “angular retrusion The patient may have “bitter smile face”, “angular arched backwardness” and other characteristic manifestations. 3. Seizure stage: the main manifestation is the persistent muscle spasm, the patient appears to have a painful expression, cyanosis, shortness of breath, hands and feet convulsions, etc., the more serious cases can be asphyxia, systemic failure and other complications. When the above manifestations occur, it is recommended that the patient consult the doctor as soon as possible, improve the auxiliary examination, in order to clarify the condition, and formulate the appropriate treatment plan for the condition.