How lymphoma will show up in the blood depends on whether the lymphoma involves the blood system or whether it involves the bone marrow. If the bone marrow is involved or the lymphoma invades the bone marrow, it can manifest as anemia, leukopenia, or thrombocytopenia. If the lymphoma transforms into leukemia, the white blood cells in the peripheral blood may be markedly increased, along with symptoms such as anemia and thrombocytopenia. In the whole body there may be fever, bone pain and other clinical manifestations, there will also be lymphoma combined with progressive weight loss, emaciation, night sweats and other so-called B symptoms. Therefore, whether lymphoma has symptoms in the blood mainly depends on whether the lymphoma invades the patient’s bone marrow.