Abdominal bloating and fatigue is most commonly associated with dyspepsia, which is common in chronic gastritis, peptic ulcer, duodenal bulb ulcer. These patients often manifest abdominal distension, fatigue, nausea and other discomforts, it is recommended that the patient further electronic gastroscopy examination, clear the cause of the active treatment to inhibit gastric acid secretion, as well as repair the gastric mucosa of the treatment. If the patient has repeated abdominal distension, fatigue, nausea and other discomforts, it is necessary to pay attention to exclude liver disease, patients with abnormal liver function often manifest abdominal distension, fatigue and other discomforts. Therefore, in the case of abdominal distension and fatigue, it is important to consider both gastric and hepatic diseases, and actively carry out e-gastroscopy and liver function tests.