There is a higher chance of hematogenous metastasis in the late stage of colon cancer. Early stage of colon cancer usually does not metastasize, but as the disease develops, blood line metastasis, plantation metastasis and lymphatic metastasis can occur in middle and late stages, and the specific percentage of blood line metastasis lacks uniform authoritative data to prove it. Hematogenous metastasis is the transfer of cancer cells to other parts of the body through blood circulation, and the most common site of metastasis is the liver, while other common sites include lungs and bones. Once colon cancer has hematogenous metastasis, it is in advanced stage, which is difficult to treat and shortens the survival period. Early detection, early diagnosis and early treatment are the keys to treat colon cancer. Meanwhile, patients should keep a good mindset, have a balanced diet and pay attention to rest. It is recommended to treat colon cancer in time after diagnosis, so as to avoid delaying the condition.