The total bilirubin is high may be the newborn baby pathologic jaundice, the hepatitis, the fatty liver and so on causes, need to take the general treatment, the drug treatment, the physical therapy and so on. 1. newborn pathological jaundice: mainly take medicine treatment, generally can take Yin gardenia yellow jaundice, at the same time, cooperate with the newborn to carry on the blue light irradiation treatment, and let the newborn drink more water, helps the jaundice to subside, reduces the total bilirubin level. 2. Hepatitis: for example, type B viral hepatitis, generally need to take antiviral medicine for disease, for example, entecavir, tenofovir. 3. Fatty liver: take lifestyle intervention, to regulate diet, avoid excessive consumption of high cholesterol foods, eat more vegetables and fruits, if fatty liver is more serious, oral statin lipid-lowering drugs, such as simvastatin, resuvastatin and so on. High total bilirubin may also be caused by other reasons, such as cholecystitis, we need to clarify the cause of the cause of the treatment with the doctor, the drug should be used according to the doctor’s instructions, do not blindly use drugs.