Chlorosartan Tablets and Chlorosartan Potassium Hydrochlorothiazide are not recommended to be used in combination, having the same drug components, the combined use may increase the adverse effects of the drug. Chlorosartan potassium belongs to the inhibition of angiotensin II receptor drugs, the main effect is to lower blood pressure, hydrochlorothiazide belongs to the diuretic, can be diuretic to reduce the level of blood pressure, chlorosartan potassium and hydrochlorothiazide can be used in combination to increase the effect of lowering blood pressure and reduce the risk of hypokalemia. Combined use of chlorosartan potassium tablets and resartan hydrochlorothiazide is not recommended, and co-administration can increase the adverse effects of the medications, such as poor control of blood pressure levels, and it is recommended to add other medications with other mechanisms of action, such as amlodipine and metoprolol. Adverse reactions to chlorosartan potassium hydrochlorothiazide include flu-like symptoms, rhinitis, cough, edema of the lower extremities, muscle aches, thirst, electrolyte disorders, etc. It is contraindicated in women who are allergic to the components of the drug, have severe renal insufficiency, or are breastfeeding during pregnancy. It is recommended to adjust the drug under the guidance of a physician.