Urinary pain is commonly associated with urethral stones, urethritis, urinary retention, overactive bladder, etc. First of all, you should go to the hospital to clarify the cause.1, urethral stones: when a stone is stuck in the urethra and can not be discharged, the stone moves in the urethra, so it produces a painful sensation. In this case, it is recommended to consult the urology department in time. If the stone is located in the anterior urethra, you can use vascular forceps to clip the stone out; if the stone is in the posterior urethra, you can use a urethral probe to push the stone into the bladder, and then use a laser or shockwave and other energies to break up the stone, after which it will be discharged with the urine; 2, urinary retention: in layman’s terms, it is impossible to discharge the urine, and the patient may be accompanied by a small abdominal bulge, with a feeling of extreme bladder distension, accompanied by pain in the urine. The patient may also have a feeling of extreme bladder distention, accompanied by pain in urination. In this case, it is recommended to visit the emergency room. No matter what the cause of urinary retention is, a urinary catheter will be placed first to expel the excess urine from the bladder. The cause is then identified and treated symptomatically. Urinary retention is most common in middle-aged and older men and is often associated with prostate hyperplasia. For middle-aged and elderly men with recurrent urinary retention, surgical treatment is recommended if it meets the surgical indications of prostatic hyperplasia; 3. UTI: Usually there are symptoms of frequent urination, urgency, and painful urination. In addition, some patients as long as a small amount of stimulation, the desire to urinate, it is recommended that patients perform routine urinalysis. If a large number of leukocytes are found in the urine routine, treatment will be given according to the urinary tract infection, and quinolone antibiotics, such as levofloxacin, will be used routinely; 4. Overactive bladder: it is a group of symptoms due to the bladder sensory nervousness as the main group of symptoms, which mainly manifests as urinary urgency, and sometimes there may be urinary pain and urination difficulty. After diagnosis, M-blockers can be given for treatment, such as tolterodine or solifenacin.