Hypertension is currently a clinically prevalent chronic disease. Long-term hypertension affects the function of important organs and is likely to cause cardiovascular and cerebrovascular diseases, leading to an increased risk of cardiovascular and cerebrovascular diseases. High altitude and low oxygen environment will obviously affect blood pressure, and blood pressure change is a mechanism in the body’s adaptation to high altitude compensation. The International Society of Mountain Medicine considers 1520-3500 meters above sea level as high altitude. Living or traveling at high altitude can lead to elevated blood pressure, and the magnitude of the effect depends on the rate of ascent and the length of time spent on the plateau. The body has a more difficult time processing oxygen when at altitude, and blood pressure can rise as a result. But the longer a person stays at higher altitudes, the better the body adapts. A study in the American Journal of Travel Medicine claimed that they found that a group of black climbers experienced a drop in systolic blood pressure when they climbed to high altitudes. However, the systolic blood pressure of white climbers increased at higher altitudes. It is not clear what causes this difference, and it certainly may not apply to everyone. The authors speculate that the results observed in the study may be related to genetic differences, hypoxic capacity, diet and exercise, among other factors. A 2019 research paper selected 300 Chinese personnel who traveled from a 40-meter elevation area in Beijing to a high-altitude operation at 1,800 meters above sea level in Xichang from March 2018 to July 2018 to observe and compare blood pressure changes in relation to altitude. The results showed that the mean systolic blood pressure increased from 128.2 ± 24.7 mmHg to 148.5 ± 11.4 mmHg and diastolic blood pressure increased from 88.8 ± 21.9 mmHg to 98 ± 8.2 mmHg from low to high altitude, and the differences were statistically significant (P < 0.05). Conclusion Conclusion: The regional change from low to high altitude caused the increase of blood pressure in Chinese people. In fact, living in a highland area for a long period of time can have a positive effect on hypertension. Dr. James Wilkerson, an American expert in mountaineering medicine, said, "Staying at high altitudes for long periods of time inhibits the disease progression process in some hypertensive patients. On the other hand, Wilkerson also notes that high altitude can have the opposite effect on non-hypertensive patients, meaning their blood pressure can rise. Acute mountain sickness: Acute mountain sickness is a disease that can affect climbers or high altitude travelers. If you ascend too fast, you can experience hypoxia or low oxygen. The lack of oxygen causes blood vessels to constrict, raising blood pressure and causing fluid to leak into the lungs. This disease can be treated with oxygen and antihypertensive medication. Without timely altitude descent or treatment, this disease can be life-threatening. The blood pressure abnormalities that occur in low altitude people to high altitude are a pathophysiological reaction, the body's blood pressure will increase or decrease in the absence of oxygen, and organic damage will occur in the absence of continuous oxygen. Those who have no symptoms of increased blood pressure, regardless of whether the increased blood pressure is in the normal range or not, do not need to be treated, and can recover naturally from high altitude. Those who have occasional symptoms can be treated symptomatically for a short period of time. Therefore, we would like to tell you the following points: 1.People who work or travel from low altitude to high altitude will have certain changes in blood pressure, so you should pay full attention to the effects of blood pressure changes; 2.No need to be overly worried and anxious if there are no obvious uncomfortable symptoms; 3.There is an adaptation process when you go to high altitude, and physical activities cannot be the same as those in low altitude, so you should 4.Pay attention to the effect of low oxygen environment on blood pressure in high altitude areas, make adequate preparations, prepare drugs to improve low oxygen, and be prepared to rescue hypertensive emergencies; 5.If you have dizziness and headache symptoms, you must pay attention to blood pressure measurement, pay attention to rest and oxygen intake, and if blood pressure rises too much, you must take drugs to lower blood pressure and go to a place with low altitude quickly.