Valsartan hydrochlorothiazide tablets can be taken for a long time when there is a therapeutic need and no serious adverse reactions. Valsartan belongs to the specific angiotensin II receptor antagonist, which can block angiotensin action and produce antihypertensive effect, commonly used in the treatment of hypertension. Hydrochlorothiazide acts on the proximal part of the distal tubule of the kidney and belongs to the diuretic class of antihypertensive drugs. Valsartan hydrochlorothiazide tablets belong to the compound preparation, the two are used in combination, can enhance the effect of antihypertensive. The common adverse reactions of valsartan hydrochlorothiazide tablets include hypokalemia, hepatic and renal impairment, muscle pain and other conditions; the use of patients with severe hepatic and renal impairment, electrolyte disorders, pregnancy, drug allergy, renal artery stenosis, etc. is prohibited. Valsartan hydrochlorothiazide antihypertensive effect is slow and smooth, and the antihypertensive effect is powerful and stable after the blood concentration is smooth. Compared with other types of antihypertensive drugs, valsartan hydrochlorothiazide tablets have fewer adverse reactions, and have a certain protective effect on patients with hypertension combined with cardiac and renal damage, which can be taken for a long time. Drugs have certain side effects, the use of valsartan hydrochlorothiazide tablets pay attention to monitoring electrolytes, liver and kidney function.