Gout patients can use medication and nursing care when toe joint pain occurs. 1. Drugs: gout attack common site for the first metatarsophalangeal joints, patients can appear joint pain, joint swelling and other symptoms, at this time can be used colchicine and etoricoxib, celecoxib and other non-steroidal anti-inflammatory drugs for treatment, after these two kinds of drugs after the treatment of the effect of unsatisfactory or there are contraindications to the use of drugs in patients can also be used as appropriate, prednisone, methylprednisolone and other glucocorticoid therapy. 2. Nursing care: gout attack patients should try to bed rest, elevate the affected limbs, during this period should be strictly low purine diet, do not smoke, drink alcohol, increase the daily water intake. All of the above drugs need to be used under the guidance of a physician, it is recommended that gout patients to the rheumatology and immunology department of a regular hospital for detailed consultation and treatment as prescribed.