High thyroid stimulating hormones, with compensatory high T3 and T4, are normal physiological responses. If thyroid stimulating hormone levels are high but T3 and T4 levels are below the normal range, this indicates hypothyroidism and requires prompt pathological examination and subsequent treatment. If the individual’s body hormone levels are within the normal range, TSH, although elevated, will not affect the levels of other hormones. A common clinical condition that requires prompt treatment is hypothyroidism. This disorder tends to slow down the heart rate, leading to a decrease in the pumping function of the heart and causing secondary hypotension. In addition to this, it can also cause gastrointestinal and neurological pathologies and requires prompt administration of thyroid hormone medications, such as levothyroxine.