The common causes of hand thumb pain include trauma, stenosing tenosynovitis, rheumatoid arthritis, and onychomycosis. 1. Trauma: there is a history of trauma, which can cause pain due to injury or even fracture of muscles, tendons and ligaments around the thumb caused by external force. 2. Stenosing tenosynovitis: mostly occurring in the thumb, it is a sterile inflammation of the tendon sheath, which may cause pain in the fingers and difficulty in flexion and extension. 3. Rheumatoid arthritis: It is a common autoimmune disease that occurs in women and can cause bone destruction, leading to finger pain. 4. Nail groove inflammation: It is caused by finger prick, abrasion and other reasons, leading to bacterial infection such as Staphylococcus aureus, causing finger pain. Causes of hand thumb pain is more reasons, may also be related to gout, chondroma and other diseases, if the symptoms continue to be unrelieved, it is recommended to consult a doctor in a timely manner, to clarify the cause of the disease, targeted treatment.