Bitten by poisonous mosquitoes swollen very large and hard, can be relieved by ice compresses, and promptly to the hospital dermatology department, the treatment method is mainly based on drug therapy. After being bitten by poisonous mosquitoes, the venom injected into the local skin can cause inflammatory reaction around, appearing red, swollen, hot, painful, hard and other symptoms. General need can use saline local cleaning wound, and then through the cold compress or ice, so that the local vasoconstriction, can reduce the symptoms of local hardness and swelling. At the same time, follow the doctor’s instructions to use anti-inflammatory, swelling drugs, such as halomethasone ointment, Dinaid cream, etc., if necessary, oral loratadine, cetirizine and other anti-allergy drugs, can effectively reduce the toxic reaction of toxic mosquito bites. For patients with serious symptoms, intravenous infusion of calcium gluconate and other drugs for treatment. Bitten by toxic mosquitoes swollen very hard, should promptly consult a doctor according to the specific conditions of the selection of appropriate and effective drugs for treatment. At the same time, should avoid scratching, so as not to aggravate the redness, swelling, hard swelling and other symptoms.